Idiopathic Primary Ovarian Insufficiency in Adolescents

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Primary ovarian insufficiency in adolescents: a case series

BACKGROUND Primary ovarian insufficiency (POI) is characterized by 4 to 6 months of amenorrhea and elevated serum FSH and LH in females less than 40 years. Ovarian insufficiency is uncommon in pediatrics and typically results from a chromosomal abnormality or treatment for malignancy. Idiopathic POI in which no apparent precipitant is identified is even rarer. After encountering three teens wit...

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Primary Ovarian Insufficiency

Primary ovarian insufficiency or premature menopause is one of the stressful problems in women younger than 40, which may cause numerous early or late psychological and physical complications. Failure of germ cell development is associated with complete ovarian insufficiency, while their decreased number is more likely associated with partial ovarian insufficiency, which leads to secondary amen...

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Primary Ovarian Insufficiency

From the Integrative Reproductive Medi­ cine Unit, Intramural Research Program on Reproductive and Adult Endocrinology, National Institute of Child Health and Hu­ man Development, National Institutes of Health, Bethesda, MD. Address reprint requests to Dr. Nelson at the Integrative Reproductive Medicine Unit, NICHD– Intramural Research Program on Repro­ ductive and Adult Endocrinology, CRC, Rm....

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Idiopathic primary ovarian insufficiency: a study of serial hormonal profiles to assess ovarian follicular activity.

BACKGROUND Ovarian follicular activity in serial hormone profiles has been reported in up to 86% of patients with primary ovarian insufficiency (POI). In most of these studies, patients had a short duration of amenorrhea or irregular menstrual cycles which could influence the occurrence of spontaneous follicular activity. The aim was to study the incidence of follicular activity in serial hormo...

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Update on primary ovarian insufficiency.

PURPOSE OF REVIEW Despite an incidence of 1% among women under the age of 40, primary ovarian insufficiency (POI) is still poorly understood. As the variable cause and presentation of POI complicate its management, a standard regimen for treatment remains to be established. However, emerging research has provided new insight on current mainstays of treatment as well as novel management approach...

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ژورنال

عنوان ژورنال: Journal of Pediatric and Adolescent Gynecology

سال: 2017

ISSN: 1083-3188

DOI: 10.1016/j.jpag.2017.03.074